Efudex (Fluorouracil )

Common Use

Efudex (fluorouracil 5%) is used to treat precancerous and cancerous skin conditions, such as actinic keratosis and superficial basal cell carcinoma. It works by interfering with the growth of abnormal skin cells.

Dosage and Direction

Apply a thin layer to the affected skin area once or twice daily as directed by your doctor. Avoid contact with eyes, mouth, and healthy skin.

Precautions

Use sunscreen and protective clothing during treatment. Avoid excessive sun exposure. Do not apply to open wounds or mucous membranes. Inform your doctor if you are pregnant, breastfeeding, or have any skin infections.

Contraindications

Not to be used in patients allergic to fluorouracil or any of the cream’s components. Contraindicated during pregnancy and in individuals with dihydropyrimidine dehydrogenase (DPD) enzyme deficiency.

Possible Side Effect

Common side effects include redness, burning, itching, scaling, and skin irritation. Severe reactions may include blistering, ulceration, or intense inflammation.

Drug Interaction

May interact with other topical products or treatments that affect skin healing. Systemic absorption is minimal, but caution is advised when used with other chemotherapy drugs.

Missed Dose

Apply as soon as you remember. If it’s close to the next dose, skip the missed one. Do not double the dose.

Overdose

Topical overdose is unlikely. In case of accidental ingestion, seek immediate medical attention.

Storage

Store at room temperature away from light and moisture. Keep out of reach of children and pets.

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