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This medicine is a female hormone used to protect the lining of the uterus in women on estrogen replacement therapy. Progesterone may lower the risk of estrogen-related cancer of the uterus. This medicine is also used to treat women who have had menstrual periods in the past but have stopped having them because of a lack of progesterone hormone. This medicine may also be used to treat other conditions as determined by your doctor.
Follow the directions for using this medicine provided by your doctor. This medicine comes with a patient information leaflet. Read it carefully. Ask your doctor, nurse, or pharmacist any questions you may have about this medicine.
Drug Class and Mechanism
Prometrium is a form of natural progesterone. It is only available by prescription. Prometrium is the only type of progesterone that can be taken by mouth.
If you miss a dose of this medicine and are taking both a morning and evening dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Store this medicine at room temperature at 77 degrees F (25 degrees C) in a tightly-closed container, away from heat, moisture, and light. Brief storage between 59 and 86 degrees F (15 and 30 degrees C) is permitted.
Possible Side Effects
Side effects that may occur while taking this medicine include sleepiness or tiredness, dizziness, cough, nausea, vomiting, cramps, bloating, worry, irritability, diarrhea, constipation, headache, breast tenderness, stomach upset, acne, or dry mouth. If they continue or are bothersome, check with your doctor. Check with your doctor as soon as possible if you experience pain or cramping in the muscles or joints; unexplained weight changes; swelling of hands or feet; fainting; vaginal discharge; difficulty urinating or change in the amount of urine produced; or breast pain. Contact your doctor immediately if you experience fever or chills; calf/leg pain, swelling, or tenderness; unusually fast heartbeat; sharp or crushing chest pain; sudden shortness of breath; sudden leg pain; sudden severe headache, vomiting, dizziness, or fainting; vision problems or changes (including sudden, partial, or full loss of vision); numbness of an arm or a leg; severe stomach pain; one-sided weakness; slurred speech; mental or mood changes (such as severe depression, memory loss, or confusion); coughing up blood; yellowing of eyes/skin; darkening of urine; stomach pain, swelling, or tenderness; abnormal vaginal bleeding; lump in the breast; or seizure. An allergic reaction to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash, itching, swelling, severe dizziness, or trouble breathing. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.
Do not share this medicine with others for whom it was not prescribed. Do not use this medicine for other health conditions. Keep this medicine out of the reach of children. If using this medicine for an extended period of time, obtain refills before your supply runs out.