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Lozol is used to treat hypertension (high blood pressure). It also is used to eliminate fluid when the body accumulates excess fluid, such as with edema and congestive heart failure.
Lozol is taken as a single daily dose, generally in the morning before breakfast. It can be taken with or without food. Antacids have no effect on the activity of Lozol.
Drug Class and Mechanism
Lozol is a diuretic (water pill) that is primarily used for the treatment of high blood pressure. It works by preventing the kidney from reabsorbing (retaining in the body) salt and water that is destined to be eliminated in the urine. This results in increased urine output (diuresis). Lozol also is thought to reduce the salt in the smooth muscle of the walls of blood vessels. (The salt ultimately is eliminated in the urine.) The loss of salt from the muscle causes the muscle to relax, and the relaxation of the vessels results in reduced blood pressure.
If you miss a dose, take it as soon as remembered; do not take if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.
Lozol should be stored between 15 degrees C (59 degrees F) and 30 degrees C (86 degrees F).
Possible Side Effects
Dehydration may occur during lozol therapy. Hypokalemia (low blood potassium due to elimination of potassium in the urine) is one of the most common adverse effects associated with the thiazide class of diuretics and may cause abnormal cardiac rhythms. The most common symptom associated with hypokalemia is muscle weakness. Patients receiving lozol may need potassium supplements to prevent hypokalemia. Hypomagnesemia (low blood magnesium) also may occur. Other possible side effects include excessive loss of sodium (particularly of concern in elderly patients), increased cholesterol (this effect tends to diminish with continued use), increased uric acid concentrations in the blood, dizziness, lightheadedness, headache, blurred vision, tingling of the extremities, nervousness, impotence, rash, photosensitivity (skin rashes due to sunlight), fatigue, irritability, and agitation.
Do not share this medicine with others for whom it was not prescribed. Do not use this medicine for other health conditions. Keep this medicine out of the reach of children. If using this medicine for an extended period of time, obtain refills before your supply runs out.