Before you buy Carafate online
What It Does?
Carafate used for the healing of ulcers of the stomach and duodenum, as a preventive treatment of recurrent ulcers in the duodenum and the prevention of major bleeding in the stomach and duodenum.
Carafate 1000mg is equally engaged in prophylactic treatment of chronic recurrent duodenal ulcer. Prophylaxis of bleeding from ulcers and erosions in the gastric and duodenal arising in connection with major burns, neurotraumata, neurosurgery, respiratory insufficiency and multiple trauma.
How It Works?
Sucralfate is alkaline aluminum sucrose sulfate, which has a local mucosal protective effect. This mucosal protective effect arises partly through a mechanical binding to mucous membrane and through a stimulation of the factors in the mucosa that increase its resistance to harmful agents. The binding to damaged mucosa is greater than with that with the healthy tissue.
How It Is Taken?
Carafate should not be taken with meals, an interval of 1-2 hours between Carafate intake and meals is recommended.
In duodenal patients Carafate is taken in doses of 2g (10 ml) 2 times a day, at bedtime and awakening. For smaller wounds therapy typically lasts during 4 weeks of treatment, while in some cases 8 weeks of treatment may be needed, for example in smokers and in larger wounds.
In gastric ulcer patients 1g (5ml), 4 times daily (last dose at bedtime). Treatment should continue until complete healing is achieved (endoscopic examination), which normally takes place within 6-8 weeks.
Prophylactic treatment of chronic recurrent duodenal ulcer requires 1g (5ml) 2 times a day, at bedtime and awakening. This treatment should not last more than 6 months.
Is It For Me?
Hypersensitivity to sucralfate or any of the excipients is a contraindication for Carafate use. In other cases, it is up to your prescriber to determine the relevance of sucralfate therapy.
Any Drug Interactions or Incompatibilities?
Sucralfate may decrease the absorption of warfarin. Caution should be exercised and coagulation parameters should be monitored if these drugs are used concomitantly.
Sucralfate is activated in the acidic environment of the stomach. Simultaneous intake of antacids and sucralfate should be avoided. A minimum interval of 30 minutes between the intake of antacids and sucralfate recommended.
The uptake of these drugs may be reduced if taken in combination with Carafate: amitriptyline, ciprofloxacin, grepafloxacine, ketoconazole, levofloxacin, norfloxacin, ofloxacin, levothyroxine, theophylline and tetracycline. These drugs should be taken two hours before or after Carafate intake.
Carafate should not be administered while citrates (such as may occur in effervescent tablets and soft drinks) because citrate may cause increased absorption of aluminum. In people with impaired renal function have been seen encephalopathy as a result of sharply increased blood levels of aluminum, but the clinical significance in patients with normal renal function is unknown. Sucralfate should be taken at least 2 hours separately from drugs or drink that contains citrate.
What Side Effects Should I Brace Myself For?
In approximately 2% of patients treated with Carafate gastrointestinal side effects occur.
Uncommon: dry mouth, nausea
Rare: bezoar; rash, urticarial.
Small quantities of aluminum are absorbed from the digestive tract and can accumulate. Aluminium osteodystrophy, osteomalacia, encephalopathy and anemia have been reported in patients with chronic renal impairment.
Any Important Tips?
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