Aciphex is a proton pump inhibitor that is used to treat gastroesophageal reflux (GERD), stomach or upper intestine ulcer, Zollinger-Ellison syndrome, and some other conditions associated with overproduce of stomach acid and discomfort and damage it can bring.
You can buy Aciphex online at AWC Canadian Pharmacy:
Aciphex tablets are used to treat the following conditions:
Gastroesophageal reflux disease (GERD), which can include heartburn. GERD occurs when acid and food from the stomach enters the esophagus (esophagus)
Ulcers in the stomach or upper intestine (duodenum). If these wounds are infected with the bacterium Helicobacter pylori will, you also be treated with antibiotics. A combined use of Aciphex pills and antibiotics eliminates the infection and heals the wound. This treatment also prevents the infection and the wound will return.
Zollinger-Ellison syndrome when the stomach produces too much acid.
How It Works
Aciphex tablet contains the active substance rabeprazole sodium. Aciphex belongs to a group of medicines called proton pump inhibitors. They work by reducing the amount of acid produced in the stomach.
How It Is Taken
Remember that Aciphex should not be chewed or crushed, but should be swallowed whole.
Dosage and dosing schedule will depend on your condition.
Active duodenal ulcer and active benign gastric ulcer: The recommended oral dose for both active duodenal ulcer and active benign gastric ulcer is 20mg once daily in the morning.
Most patients with active duodenal ulcer heal within four weeks. Some patients may need a further four weeks of therapy to achieve healing. Most patients with active benign gastric ulcer heal within six weeks. However, even here a few patients may need additional six weeks of therapy to achieve healing.
Erosive or ulcerative gastroesophageal reflux disease (GERD): The recommended oral dose for this condition is 20mg daily for four to eight weeks.
Long-term treatment of gastroesophageal reflux disease (GORD Maintenance): For long-term treatment, Aciphex 20mg or 10mg given daily, depending on how the patient responds to treatment.
Symptomatic treatment of moderate to very severe gastro-oesophageal reflux disease: 10mg once daily in patients without esophagitis. If symptoms has not been achieved after 4 weeks, the patient should be further investigated. Since the symptoms subsided, reoccurring symptoms can be treated by the demand treatment, with the dose of 10mg once daily as needed.
Zollinger-Ellison syndrome: The recommended starting dose for adults is 60mg once daily. The dose may be titrated up to 120mg per day, tailored to the individual patient. Doses up to 100mg can be given once daily. For dose 120mg may be required in divided doses of 60mg 2 times daily. Treatment should continue as long as clinically indicated.
Is It For Me?
Aciphex is contraindicated in patients with known hypersensitivity to rabeprazole sodium or any of the other ingredients of the formulation. Aciphex is contraindicated during pregnancy and lactation.
Any Drug Interactions or Incompatibilities?
Rabeprazole sodium gives heavy and prolonged inhibition of acid secretion in the stomach.
Interactions with substances whose absorption is pH dependent may occur. Co-administration of rabeprazole sodium with ketoconazole and itraconazole may result in a significant reduction in plasma levels of these agents. Some patients may need to be monitored to determine if dose adjustment is needed when ketoconazole and itraconazole are taken concomitantly with Aciphex.
What Side Effects Should I Brace Myself For?
Any Important Tips?
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Aciphex - contraindications, warnings and precautions
Relief of symptoms after treatment with rabeprazole sodium does not exclude gastric or esophageal malignancy. For this reason, malignancy should be excluded before treatment with Aciphex begins.
Patients on long-term treatment (particularly those treated for longer than one year) should be checked regularly.
The risk of cross sensitivity with other proton pump inhibitor or substituted benzimidazoles should not be excluded.
Aciphex should not be given to children because of lack of respective studies.
There are reports from the clinical use of blood dyscrasias (thrombocytopenia and neutropenia). In the majority of cases where an alternative cause could not be identified were cases uncomplicated and disappeared after discontinuation of rabeprazole.
There were observed liver enzyme changes in clinical studies and in clinical use. In the majority of cases where an alternative cause could not be identified and symptoms disappeared after discontinuation of rabeprazole.
No data to suggest a significant drug related safety problems have been observed in studies in patients with mild to moderate hepatic impairment, compared to age- and sex-matched healthy controls. Since clinical data on the use of Aciphex in patients with severe hepatic impairment, the prescriber should, however, exercise caution when treatment with Aciphex is initiated in these patients.
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